BDBM50519013 CHEMBL4452383

SMILES CCc1sc2ncnc(N[C@H](Cc3ccccc3OCCN3CCN(C)CC3)C(O)=O)c2c1-c1cccc(Cl)c1C

InChI Key InChIKey=BNEPHKHHSLGKJV-XMMPIXPASA-N

Data  1 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50519013   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50519013(CHEMBL4452383)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of N-terminal fluorescein labelled Puma-BH3 peptide from TEV-fused His-tagged human Mcl-1 expressed in Escherichia coliBL21(DE3) pLysS c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry

Curated by ChEMBL
LigandPNGBDBM50519013(CHEMBL4452383)
Affinity DataKd:  360nMAssay Description:Binding affinity to TEV-fused His-tagged human Mcl-1 expressed in Escherichia coliBL21(DE3) pLysS cells by Isothermal Titration CalorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed