BDBM50519022 CHEMBL4472351
SMILES CCc1sc2ncnc(O[C@H](Cc3ccccc3)C(O)=O)c2c1-c1ccc(OCCN2CCN(C)CC2)c(Cl)c1C
InChI Key InChIKey=ORTDLNZBBWXSKF-XMMPIXPASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50519022
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Affinity DataKi: 2.50E+4nMAssay Description:Displacement of N-terminal fluorescein labelled Puma-BH3 peptide from TEV-fused His-tagged human Mcl-1 expressed in Escherichia coliBL21(DE3) pLysS c...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Affinity DataKi: 2.50E+4nMAssay Description:Displacement of N-terminal fluorescein labelled Puma-BH3 peptide from TEV-fused His-tagged human Mcl-1 expressed in Escherichia coliBL21(DE3) pLysS c...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Affinity DataKd: 30nMAssay Description:Binding affinity to TEV-fused His-tagged human Mcl-1 expressed in Escherichia coliBL21(DE3) pLysS cells by Isothermal Titration CalorimetryMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Affinity DataKd: 10nMAssay Description:Binding affinity to TEV-fused His-tagged human Mcl-1 expressed in Escherichia coliBL21(DE3) pLysS cells by SPR analysisMore data for this Ligand-Target Pair