BDBM50519425 CHEMBL4460341

SMILES CC(C)(C)C(=O)Nc1cc(Oc2ccc(Nc3nccc4[nH]cc(-c5ccc(F)cc5)c(=O)c34)cc2F)ccn1

InChI Key InChIKey=TYKHTTFXUAFZDN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50519425   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50519425(CHEMBL4460341)
Affinity DataIC50:  28nMAssay Description:Inhibition of purified recombinant MET kinase domain (unknown origin) using biotin as substrate preincubated for 5 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50519425(CHEMBL4460341)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of purified recombinant VEGFR2 kinase domain (unknown origin) using biotin as substrate preincubated for 5 mins followed by substrate addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed