BDBM50519473 CHEMBL4546097

SMILES Cn1c2nc(Oc3cccc(Cl)c3)n(Cc3ccc(Cl)cc3)c2c(=O)n(CCCO)c1=O

InChI Key InChIKey=VYJPVPHNGWEIBT-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50519473   

TargetShort transient receptor potential channel 5(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519473(CHEMBL4546097)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of human TRPC5 expressed in human T-REx-293 cells assessed as reduction in calcium influx by Fluo-4AM dye based assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 4(Homo sapiens)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519473(CHEMBL4546097)
Affinity DataIC50:  46nMAssay Description:Inhibition of human TRPC4 expressed in human T-REx-293 cells coexpressing M1 receptor assessed as reduction in calcium influx by Fluo-4AM dye based a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519473(CHEMBL4546097)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of human TRPC5 expressed in human T-REx-293 cells assessed as reduction in lanthanum-activated TRPC5-mediated currents by whole-cell patch...More data for this Ligand-Target Pair