BDBM50519633 CHEMBL4592472
SMILES COc1cc(c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12)S(=O)(=O)CCN(C)C
InChI Key InChIKey=UZTKORAJTJRUTJ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50519633
Affinity DataIC50: 195nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R mutant expressed in baculovirus expression system using Tyr 04 as substrate incubated for...More data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus expression system using Tyr 04 as substrate incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant expressed in baculovirus expression system using Tyr 04 as substrate incubated for 1 hr ...More data for this Ligand-Target Pair