BDBM50519636 BMN 195::BMN-195::Ezutromid::SMT-C1100::SMTC-1100::Smt c1100

SMILES CCS(=O)(=O)c1ccc2oc(nc2c1)-c1ccc2ccccc2c1

InChI Key InChIKey=KSGCNXAZROJSNW-UHFFFAOYSA-N

Data  1 IC50  1 Kd  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50519636   

TargetUtrophin(Homo sapiens)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50519636(BMN 195 | BMN-195 | Ezutromid | SMT-C1100 | SMTC-1...)
Affinity DataEC50:  110nMAssay Description:Activation of human utrophin-1 in mouse mdx myoblasts by H2K-mdx utrnA-luc assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50519636(BMN 195 | BMN-195 | Ezutromid | SMT-C1100 | SMTC-1...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50519636(BMN 195 | BMN-195 | Ezutromid | SMT-C1100 | SMTC-1...)
Affinity DataKd:  50nMAssay Description:Binding affinity to AhR (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUtrophin(Homo sapiens)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50519636(BMN 195 | BMN-195 | Ezutromid | SMT-C1100 | SMTC-1...)
Affinity DataEC50:  187nMAssay Description:Modulation of human utrophinA expressed in mouse H2K cells assessed as upregulation of utrophin production after 24 hrs by luciferase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUtrophin(Homo sapiens)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50519636(BMN 195 | BMN-195 | Ezutromid | SMT-C1100 | SMTC-1...)
Affinity DataEC50:  1.28E+3nMAssay Description:Activation of human utrophin-1 in iDMD cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed