BDBM50520683 CHEMBL4476621
SMILES Oc1ccccc1C(=O)NNC(=S)Nc1ccc(Cl)c(Cl)c1
InChI Key InChIKey=FNTHJTUPRVAXFZ-UHFFFAOYSA-N
Data 21 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50520683
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli using 3-phosphoglycerate as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant Arg1 using L-arginine as substrate after 5 mins in presence of [guanidino-14C]-L-arginine by liquid scintillation cou...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human carbonic anhydrase 2 using 4-nitrophenyl acetate as substrate after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Displacement of [3H]muscimol from recombinant human GABAalpha1beta2gamma2 measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant Lck using Ulight-Poly GAT[EAY(1:1:1)]n as substrate after 10 mins by LANCE analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 363nMAssay Description:Inhibition of human MAGLMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human MAOA using kynuramine as substrate after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant PDE3A using [3H]cAMP after 20 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]-Dofetilide from recombinant human ERG after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Displacement of [3H]WY 14643 from human recombinant PPARalpha receptor at 10 uM after 120 mins by scintillation counting analysis relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant ACE using Abz-FRK(Dnp)-P-OH as substrate after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human IDO using L-tryptophan as substrate after 30 mins by Ehrlich's reagent based assayMore data for this Ligand-Target Pair
TargetD-alanine--D-alanine ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of Enterococcus faecalis JH2-2 C-terminal 6His-tagged DdlB expressed in Escherichia coli LMG194 preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant acetylcholinesterase using acetylthiocholine as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant COX1 using arachidonic acid as substrate after 3 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]pirenzepine from human recombinant M1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetO15496/P04054/P14555/P39877/Q5R387/Q9BX93/Q9BZM1/Q9BZM2/Q9NZ20/Q9NZK7/Q9UNK4(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human sPLA2More data for this Ligand-Target Pair
Affinity DataIC50: 0.103nMAssay Description:Inhibition of human thrombin using Z-GPR-AMC as substrate after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Displacement of [3H]CP 55940 from human recombinant CB1 receptor after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.77E+5nMAssay Description:Inhibition of human recombinant full-length LDHA using sodium pyruvate as substrate after 60 mins by resazurin dye-based assayMore data for this Ligand-Target Pair