BDBM50521245 CHEMBL4547187

SMILES [H][C@]12CC[C@]([H])(CN(C1)c1ncnc(C)c1F)[C@H]2Nc1nc2N(CCCn2n1)c1cccc(F)c1

InChI Key InChIKey=SLAWDKYXFFJMLG-CWPLJXCYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50521245   

TargetPresenilin-1(Homo sapiens (Human))
Temple University School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50521245(CHEMBL4547187)
Affinity DataEC50:  0.0130nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in amyloid beta-42 secretion by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed