BDBM50521600 CHEMBL4558749

SMILES CCC#CC[C@H](C)[C@H](O)\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O

InChI Key InChIKey=CBIUADIJQPJQEZ-VIDOSBHOSA-N

Data  3 KI  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50521600   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50521600(CHEMBL4558749)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50521600(CHEMBL4558749)
Affinity DataKi:  880nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP3 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50521600(CHEMBL4558749)
Affinity DataKi:  1.22E+4nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP2 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50521600(CHEMBL4558749)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP2 receptor expressed in HEK293T/17 cells assessed as increase in GalphaS-mediated CREB activation measured after 6 to 24 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50521600(CHEMBL4558749)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP2 receptor expressed in HEK293T/17 cells assessed as increase in intracellular cAMP level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50521600(CHEMBL4558749)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells assessed as reduction in tail current amplitude by automated patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50521600(CHEMBL4558749)
Affinity DataEC50:  0.476nMAssay Description:Agonist activity at human EP4 receptor expressed in HEK293T/17 cells assessed as increase in GalphaS-mediated CREB activation measured after 6 to 24 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50521600(CHEMBL4558749)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human EP4 receptor expressed in HEK293T/17 cells assessed as increase in intracellular cAMP level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed