BDBM50523275 CHEMBL4537026

SMILES O=C(Nc1cccc(n1)-c1cn(CCNc2c3CCCCc3nc3ccccc23)nn1)Nc1cccc2C(=O)N3CCCCC3c12

InChI Key InChIKey=JRYNVBKKSAGWOO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50523275   

TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50523275(CHEMBL4537026)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate in presence of [gamma-33P]ATP incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50523275(CHEMBL4537026)
Affinity DataIC50:  21nMAssay Description:Inhibition of human serum BChE using BTCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellman's me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50523275(CHEMBL4537026)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50523275(CHEMBL4537026)
Affinity DataIC50:  133nMAssay Description:Inhibition of human recombinant AChE using ATCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed