BDBM50523865 CHEMBL4476495
SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1ccnc1
InChI Key InChIKey=QDBAGSYNQOBNDU-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50523865
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu3 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu4 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+3nMAssay Description:Negative allosteric modulation of mGlu7 (unknown origin) in cells expressing G protein-regulated inwardly rectifying potassium channels (GIRKs) asses...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu5 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu6 receptor (unknown origin)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 501nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataIC50: 501nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Negative allosteric modulation of mGlu7 (unknown origin) in cells expressing G protein-regulated inwardly rectifying potassium channels (GIRKs) asses...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu8 receptor (unknown origin)More data for this Ligand-Target Pair