BDBM50523865 CHEMBL4476495

SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1ccnc1

InChI Key InChIKey=QDBAGSYNQOBNDU-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50523865   

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523865(CHEMBL4476495)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu1 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523865(CHEMBL4476495)
Affinity DataIC50:  570nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523865(CHEMBL4476495)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523865(CHEMBL4476495)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu3 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523865(CHEMBL4476495)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu4 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523865(CHEMBL4476495)
Affinity DataIC50:  3.16E+3nMAssay Description:Negative allosteric modulation of mGlu7 (unknown origin) in cells expressing G protein-regulated inwardly rectifying potassium channels (GIRKs) asses...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523865(CHEMBL4476495)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu5 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523865(CHEMBL4476495)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu6 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523865(CHEMBL4476495)
Affinity DataIC50:  501nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523865(CHEMBL4476495)
Affinity DataIC50:  501nMAssay Description:Negative allosteric modulation of rat mGlu7 in HEK cells expressing Galpha15 assessed as inhibition of L-AP4-induced response measured by calcium mob...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523865(CHEMBL4476495)
Affinity DataIC50:  3.00E+3nMAssay Description:Negative allosteric modulation of mGlu7 (unknown origin) in cells expressing G protein-regulated inwardly rectifying potassium channels (GIRKs) asses...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50523865(CHEMBL4476495)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of mGlu8 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed