BDBM50524149 CHEMBL4436821

SMILES CC(Cl)C(=O)Nc1c(cnn1-c1ccc(cc1)S(N)(=O)=O)C#N

InChI Key InChIKey=RLCSMEASWTXBRD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524149   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50524149(CHEMBL4436821)
Affinity DataIC50:  507nMAssay Description:Inhibition of human recombinant COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated with enzyme for 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50524149(CHEMBL4436821)
Affinity DataIC50:  108nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated with enzyme for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed