BDBM50525011 CHEMBL4569780::US11401286, Example 119
SMILES NC(=O)CCc1ccc(Nc2cc(nc3CCCc23)-c2cccc(Cl)c2)cc1
InChI Key InChIKey=FYDGODWYUZSZIB-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50525011
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 166nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
TargetIsoform 7 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Tetra Discovery Partners
US Patent
Tetra Discovery Partners
US Patent
Affinity DataIC50: >1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B [S133D](Homo sapiens (Human))
Tetra Discovery Partners
US Patent
Tetra Discovery Partners
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair