BDBM50525246 CHEMBL4522006

SMILES Oc1cc2nc(NC(=O)c3ccccc3Sc3ccc(cc3)C(F)(F)F)sc2cc1O

InChI Key InChIKey=WGUPAQJNOSUNBA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50525246   

TargetGenome polyprotein(Dengue virus 2)
Queensland University Of Technology

Curated by ChEMBL
LigandPNGBDBM50525246(CHEMBL4522006)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of His-tagged DENV2 NS2B-NS3 serine protease expressed in Escherichia coli BL21 using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
Queensland University Of Technology

Curated by ChEMBL
LigandPNGBDBM50525246(CHEMBL4522006)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of DENV3 NS2B-NS3 protease using PhAc-Lys-Arg-Arg-AMC as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGenome polyprotein(Dengue virus 2)
Queensland University Of Technology

Curated by ChEMBL
LigandPNGBDBM50525246(CHEMBL4522006)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGenome polyprotein(Dengue virus 2)
Queensland University Of Technology

Curated by ChEMBL
LigandPNGBDBM50525246(CHEMBL4522006)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of GST-tagged DENV3 NS2B-NS3 serine protease expressed in Escherichia coli BL21Gold(DE3) using Boc-Gly-Arg-Arg-7-amino-4-methylcoumarin as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed