BDBM50525496 CHEMBL4449189
SMILES Fc1ccc(cc1)C(=O)CSc1nccc(Nc2ccc(cc2)N2CCOCC2)n1
InChI Key InChIKey=PSZMYZPRCFMLOG-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50525496
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of PDGFR beta (unknown origin)More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of RAF1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of TIE2 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human wild type BRAF by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair