BDBM50525508 CHEMBL4549103

SMILES COc1ccc(cc1)C(=O)CSc1nccc(Nc2ccc(cc2)N2CCOCC2)n1

InChI Key InChIKey=PAFWXQKNFNRYSJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50525508   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525508(CHEMBL4549103)
Affinity DataIC50:  440nMAssay Description:Inhibition of human wild type BRAF by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525508(CHEMBL4549103)
Affinity DataIC50:  290nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed