BDBM50525511 CHEMBL4573547

SMILES CCOC(=O)c1ccc(Nc2ccnc(SCC(=O)c3ccc(cc3)C#N)n2)cc1

InChI Key InChIKey=DLNAZINCLYSSMT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50525511   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525511(CHEMBL4573547)
Affinity DataIC50:  390nMAssay Description:Inhibition of PDGFR beta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525511(CHEMBL4573547)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of TIE2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525511(CHEMBL4573547)
Affinity DataIC50:  170nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525511(CHEMBL4573547)
Affinity DataIC50:  410nMAssay Description:Inhibition of RAF1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525511(CHEMBL4573547)
Affinity DataIC50:  280nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525511(CHEMBL4573547)
Affinity DataIC50:  5.16E+3nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50525511(CHEMBL4573547)
Affinity DataIC50:  150nMAssay Description:Inhibition of human wild type BRAF by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed