BDBM50526581 CHEMBL4466169::US11459335, Compound 14::US20230279023, Compound 14

SMILES O=C1CCC(Nc2ccccc2N2CCOCC2)C(=O)N1

InChI Key InChIKey=WBYAHIPMCICAIV-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50526581   

TargetProtein cereblon(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50526581(CHEMBL4466169 | US11459335, Compound 14 | US202302...)
Affinity DataKd:  1.00E+4nMAssay Description:Displacement of (-)-thalidomide-alexa fluor/pomalidomide-fluorescein conjugated probe from DDBI fused CRBN (unknown origin) measured after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM50526581(CHEMBL4466169 | US11459335, Compound 14 | US202302...)
Affinity DataKd:  3.00E+4nMAssay Description:Measuring compound ligand binding to CRBN-DDB1 was carried out using an established sensitive and quantitative in vitro fluorescence polarization (FP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
C4 Therapeutics

US Patent
LigandPNGBDBM50526581(CHEMBL4466169 | US11459335, Compound 14 | US202302...)
Affinity DataKd:  3.00E+4nMAssay Description:Measuring compound ligand binding to CRBN-DDB1 was carried out using an established sensitive and quantitative in vitro fluorescence polarization (FP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent