BDBM50526873 CHEMBL4461592

SMILES Fc1cc(NC(=O)Nc2ccc(Cl)cn2)cc(c1)C#N

InChI Key InChIKey=KDANLHLWAYNCMV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50526873   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526873(CHEMBL4461592)
Affinity DataIC50:  13nMAssay Description:Inhibition of rat mGluR5 expressed in HEK293A cells preincubated for 140 secs followed by EC20 glutamate stimulation for 74 secs and subsequent EC80 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526873(CHEMBL4461592)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of mGluR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526873(CHEMBL4461592)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of mGluR3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526873(CHEMBL4461592)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of mGluR7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526873(CHEMBL4461592)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of mGluR8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526873(CHEMBL4461592)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of mGluR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50526873(CHEMBL4461592)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of mGluR4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed