BDBM50526963 CHEMBL4456922

SMILES Cc1cc(cn(C)c1=O)-c1nc2ccccc2n1CC1CCOCC1

InChI Key InChIKey=IWELMDBRVJWCNU-UHFFFAOYSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50526963   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50526963(CHEMBL4456922)
Affinity DataIC50:  79nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBromodomain adjacent to zinc finger domain protein 2A(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50526963(CHEMBL4456922)
Affinity DataIC50:  316nMAssay Description:Inhibition of BAZ2A (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed