BDBM50527653 CHEMBL4527606
SMILES Nc1nn(-c2ccc3cn[nH]c3c2)c2cc(cnc12)-c1ccnn1Cc1ccc(Cl)cc1Cl
InChI Key InChIKey=ZTSBSKOYWGNDHO-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50527653
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human liver microsome CYP2C9 using diclofenac as substrate incubated for 5 to 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human liver microsome CYP1A2 using phenacetin as substrate incubated for 5 to 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human liver microsome CYP2D6 using dextromethorphan as substrate incubated for 5 to 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human liver microsome CYP3A4 using midazolam as substrate incubated for 5 to 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human CD73 expressed in CHO cells in 2 % DMSO using AMP as substrate preincubated for 60 mins followed by substrate additio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human liver microsome CYP2C19 using S-mephenytoin as substrate incubated for 5 to 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair