BDBM50527929 CHEMBL4455633

SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cncc(c1)-c1cccc2[nH]ccc12

InChI Key InChIKey=KKMZWHRTQLNOCF-UHFFFAOYSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50527929   

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50527929(CHEMBL4455633)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of GST-tagged recombinant PI5P4Kbeta (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Homo sapiens)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50527929(CHEMBL4455633)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of GST-tagged recombinant PI5P4Kalpha (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50527929(CHEMBL4455633)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Homo sapiens)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50527929(CHEMBL4455633)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by bioluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50527929(CHEMBL4455633)
Affinity DataKd:  3.40nMAssay Description:Binding affinity to human PI5P4IKgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed