BDBM50528069 CHEMBL4459426::US11634404, Compound 20
SMILES Cc1ccc2cc([nH]c2c1)C(=O)N1CCN(CCOc2cccnc2)CC1
InChI Key InChIKey=ZAVNMUPCFJDCTL-UHFFFAOYSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50528069
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute Of Neurological Disorders And Stroke
Curated by ChEMBL
National Institute Of Neurological Disorders And Stroke
Curated by ChEMBL
Affinity DataEC50: 4.30nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataEC50: 138nMAssay Description:For a secondary-screen and selectivity assays, DAR PathHunter® βarrestin GPCR cell lines from DiscoverX (Fremont, Calif.) were used. In the D2 R...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataEC50: 4.30nMAssay Description:Compounds were tested for their ability to compete with the orthosteric radioligand [3H]methylspiperone for binding to the D3 DAR using stable HEK ce...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataEC50: 138nMAssay Description:Agonist activity at human D2R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair