BDBM50528483 CHEMBL4448450

SMILES Clc1ccc(Cn2cc(C(=O)N\N=C\c3ccc(cc3)C#N)c3ccccc23)cc1

InChI Key InChIKey=QFILWQMENLVEBA-MZJWZYIUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50528483   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50528483(CHEMBL4448450)
Affinity DataIC50:  7.59E+3nMAssay Description:Inhibition of recombinant human COX2 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50528483(CHEMBL4448450)
Affinity DataIC50:  3.92E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed