BDBM50528722 CHEMBL4453847

SMILES O=C(N[C@H]1CN2CCC1CC2)c1cc2ccc3ccccc3n2c1

InChI Key InChIKey=QWJGFXHJEQDQOM-SFHVURJKSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50528722   

Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528722(CHEMBL4453847)
Affinity DataIC50:  710nMAssay Description:Antagonist activity at human 5-HT3A receptor expressed in Xenopus laevis oocytes at -90 mV holding potential in presence of serotonin by two-electrod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528722(CHEMBL4453847)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes preincubated with 1 uM alpha7 type-2 PAM PNU-120596 at -90 mV holding pote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528722(CHEMBL4453847)
Affinity DataIC50:  1.01E+4nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528722(CHEMBL4453847)
Affinity DataEC50:  6.14E+3nMAssay Description:Agonist activity at alpha4beta2 nAChR (unknown origin) expressed in Xenopus laevis oocytes at -90 mV holding potential by two-electrode voltage clamp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528722(CHEMBL4453847)
Affinity DataEC50:  1.88E+3nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as induction of channel current at -90 mV holding potential by tw...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50528722(CHEMBL4453847)
Affinity DataIC50:  21nMAssay Description:Induction of desensitization at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine induced current treate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed