BDBM50528946 CHEMBL4459197

SMILES COCc1ccc(C(O)=O)c(NC(=O)c2ccc(Cc3c[nH]c4nc(N)[nH]c(=O)c34)cc2)c1

InChI Key InChIKey=ZEGLZVITHYSRPB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50528946   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Yale University

Curated by ChEMBL
LigandPNGBDBM50528946(CHEMBL4459197)
Affinity DataIC50:  390nMAssay Description:Inhibition of recombinant human His6-tagged TS using dUMP and 5,10-methylenetetrahydrofolate as substrate by spectrometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Yale University

Curated by ChEMBL
LigandPNGBDBM50528946(CHEMBL4459197)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of recombinant Cryptosporidium hominis TS-DHFR expresssed in Escherichia coli PA414 using dUMP and 5,10-methylenetetrahydrofolate as subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed