BDBM50528961 CHEMBL4435747

SMILES Ic1ccc(CSc2nnc(-c3ccccn3)n2Cc2ccccn2)cc1

InChI Key InChIKey=SRZATJYBFFQUIN-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50528961   

TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50528961(CHEMBL4435747)
Affinity DataEC50:  76nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50528961(CHEMBL4435747)
Affinity DataEC50:  107nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) assessed as effect on ERK2 phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50528961(CHEMBL4435747)
Affinity DataEC50:  1.01E+4nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) assessed as increase in beta arrestin 2 recruitmentMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50528961(CHEMBL4435747)
Affinity DataEC50:  107nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) assessed as effect on ERK1 phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed