BDBM50529071 CHEMBL4471208

SMILES Fc1ccc(N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2)c(c1)-c1ccsc1

InChI Key InChIKey=XHQOFWMFUCKWSM-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50529071   

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50529071(CHEMBL4471208)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50529071(CHEMBL4471208)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50529071(CHEMBL4471208)
Affinity DataIC50:  4nMAssay Description:Inhibition of rat synaptosomes 5HT transporter assessed as reduction in [3H]serotonin reuptake incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed