BDBM50529074 CHEMBL4574299

SMILES Fc1ccc2[nH]cc(CCN3CCN(CC3)c3nsc4ccccc34)c2c1

InChI Key InChIKey=IQLAXZNATZKPMO-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50529074   

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50529074(CHEMBL4574299)
Affinity DataKi:  0.990nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50529074(CHEMBL4574299)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
China State Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50529074(CHEMBL4574299)
Affinity DataIC50:  23nMAssay Description:Inhibition of rat synaptosomes 5HT transporter assessed as reduction in [3H]serotonin reuptake incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed