BDBM50529328 CHEMBL4475441

SMILES COc1cccn(CC(=O)NCCc2ccc(cc2)-c2ccccc2)c1=S

InChI Key InChIKey=DHHBMHIBSJVIFD-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50529328   

TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50529328(CHEMBL4475441)
Affinity DataKi:  8.70E+3nMAssay Description:Competitive inhibition of human recombinant IRAP expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50529328(CHEMBL4475441)
Affinity DataKi:  1.74E+4nMAssay Description:Competitive inhibition of human recombinant ERAP2 expressed in baculovirus infected sf9 cells using R-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50529328(CHEMBL4475441)
Affinity DataKi:  2.34E+4nMAssay Description:Competitive inhibition of human recombinant ERAP1 expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50529328(CHEMBL4475441)
Affinity DataIC50:  3.19E+4nMAssay Description:Inhibition of human recombinant ERAP2 expressed in baculovirus infected Sf9 cells using omniMMP fluorogenic substrate incubated for 5 to 10 mins by f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50529328(CHEMBL4475441)
Affinity DataIC50:  2.56E+4nMAssay Description:Inhibition of human recombinant ERAP1 expressed in baculovirus infected Sf9 cells using omniMMP fluorogenic substrate incubated for 5 to 10 mins by f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Homo sapiens)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50529328(CHEMBL4475441)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of human recombinant IRAP expressed in baculovirus infected Sf9 cells using omniMMP fluorogenic substrate incubated for 5 to 10 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed