BDBM50529408 CHEMBL4451788

SMILES CC(C)n1nc(-c2ccc3oc(N)nc3c2)c2c1nc([nH]c2=O)N(C)C

InChI Key InChIKey=QBANGRVBRXSUJZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50529408   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50529408(CHEMBL4451788)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of human recombinant GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus expression system using GFP-4E-BP1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50529408(CHEMBL4451788)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed