BDBM50529472 CHEMBL4578499

SMILES CNC(=O)c1ccccc1Nc1nc(Nc2ccc(CNC(=O)C=C)cc2OC)nc2[nH]ccc12

InChI Key InChIKey=XXVNXOABVWEYIY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50529472   

TargetG protein-coupled receptor kinase 5(Bos taurus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50529472(CHEMBL4578499)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of bovine GRK5 C474S mutant using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Bos taurus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50529472(CHEMBL4578499)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of bovine GRK2 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetG protein-coupled receptor kinase 5(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50529472(CHEMBL4578499)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of human GRK5 using tubulin as substrate measured after 4 hrs by [gamma-32P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed