BDBM50529668 Enobosarm::Gtx-024::MK-2866::Ostarine::US10806720, Compound Enobosarm-(agonist)::US11230523, Compound Enobosarm-(agonist)::US11648234, Compound Enobosarm-(agonist)
SMILES C[C@](O)(COc1ccc(cc1)C#N)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F
InChI Key InChIKey=JNGVJMBLXIUVRD-SFHVURJKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50529668
Affinity DataKi: 0.550nMAssay Description:Displacement of [3H]mibolerone from Androgen receptor (unknown origin) measured by liquid scintillation counting methodMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 3.80nMAssay Description:Displacement of [3H]-mibolerone from recombinant wild-type GST-tagged androgen receptor LBD (unknown origin) after 16 hrs by scintillation counting a...More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Displacement of [3H]-mibolerone from recombinant wild-type GST-tagged androgen receptor LBD (unknown origin) after 16 hrs by scintillation counting a...More data for this Ligand-Target Pair
Affinity DataKi: 20.2nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
TargetAndrogen receptor [633-919](Homo sapiens (Human))
University of Tennessee Research Foundation
US Patent
University of Tennessee Research Foundation
US Patent
Affinity DataKi: 20.2nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
TargetAndrogen receptor [633-919](Homo sapiens (Human))
University of Tennessee Research Foundation
US Patent
University of Tennessee Research Foundation
US Patent
Affinity DataKi: 20.2nMAssay Description:hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD was combin...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
School Of Pharmacy And Pharmaceutical Sciences
Curated by ChEMBL
School Of Pharmacy And Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Antagonist activity at rat androgen receptor fused with DNA-binding domain of GAL4 expressed in AR-UAS-bla GripTite 293 cells assessed as inhibition ...More data for this Ligand-Target Pair
TargetAndrogen receptor [633-919](Homo sapiens (Human))
University of Tennessee Research Foundation
US Patent
University of Tennessee Research Foundation
US Patent
Affinity DataIC50: 20nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of R1881-induced receptor transactivation after 24 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of R1881-induced receptor transactivation after 24 hr...More data for this Ligand-Target Pair