BDBM50529938 CHEMBL259388

SMILES [#6]-c1nc2sccn2c(=O)c1-[#6]-[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\c1ccccc1)-c1ccc(F)cc1

InChI Key InChIKey=MFVJXLPANKSLLD-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50529938   

TargetDiacylglycerol kinase alpha(Sus scrofa)
University Of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of pig FLAG3-tagged DGKalpha expressed in African green monkey COS7 cells using 1,2-dioleoyl-sn-glycerol as substrate measured after 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Homo sapiens)
University Of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates using DAG as substrate measured after 5 mins in presence of [ga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Rattus norvegicus)
University Of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of rat FLAG-tagged DGKalpha expressed in HEK293T cells using DAG as substrate measured after 15 mins in presence of [gamma-32P]ATP by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Homo sapiens)
University Of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of OST-tagged DGKalpha (unknown origin) expressed in MDCK cell homogenates using DAG as substrate measured after 5 mins in presence of [ga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Rattus norvegicus)
University Of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of rat FLAG-tagged DGKalpha expressed in HEK293T cells using DAG as substrate measured after 15 mins in presence of [gamma-32P]ATP by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Homo sapiens)
University Of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Sus scrofa)
University Of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of pig FLAG3-tagged DGKalpha expressed in African green monkey COS7 cells using 1,2-dioleoyl-sn-glycerol as substrate measured after 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol kinase alpha(Homo sapiens)
University Of Piemonte Orientale

Curated by ChEMBL
LigandPNGBDBM50529938(CHEMBL259388)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of DGKalpha in human erythrocytes using OAG as substrate preincubated for 1 min followed by OAG addition and measured after 8 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed