BDBM50532184 CHEMBL4526802

SMILES CCc1ccc(COc2ccc(cc2OC)C2CN(C2)C(=O)c2cc(COCC(CO)(CO)CO)ccn2)cc1

InChI Key InChIKey=JHTYCUBQAVGVTP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50532184   

TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50532184(CHEMBL4526802)
Affinity DataIC50:  35nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50532184(CHEMBL4526802)
Affinity DataIC50:  17nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed