BDBM50532184 CHEMBL4526802
SMILES CCc1ccc(COc2ccc(cc2OC)C2CN(C2)C(=O)c2cc(COCC(CO)(CO)CO)ccn2)cc1
InChI Key InChIKey=JHTYCUBQAVGVTP-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50532184
Affinity DataIC50: 35nMAssay Description:Inhibition of CSF1R in CSF1-induced DBA/1J mouse BMMC assessed as reduction in LPS-induced IL6 production preincubated for overnight followed by LPS-...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human CSF1R tyrosine kinase domain (538 to 972 residues) using Poly(Glu, Tyr)-biotinylated peptide as substrate preincubated for 5 mins...More data for this Ligand-Target Pair