BDBM50532210 CHEBI:67078::DELTA9-TETRAHYDROCANNABINOLIC ACID A

SMILES [H][C@@]12CCC(C)=C[C@@]1([H])c1c(O)c(C(O)=O)c(CCCCC)cc1OC2(C)C

InChI Key InChIKey=UCONUSSAWGCZMV-HZPDHXFCSA-N

Data  3 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50532210   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50532210(CHEBI:67078 | DELTA9-TETRAHYDROCANNABINOLIC ACID A)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-CP55940 from recombinant human CB1 receptor expressed in Sf9 cell membranes co-expressing Galphai3beta1gamma2 measured after 90 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50532210(CHEBI:67078 | DELTA9-TETRAHYDROCANNABINOLIC ACID A)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]-CP55940 from recombinant human CB2 receptor expressed in Sf9 cell membranes co-expressing Galphai3beta1gamma2 measured after 90 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50532210(CHEBI:67078 | DELTA9-TETRAHYDROCANNABINOLIC ACID A)
Affinity DataKi:  6.50E+3nMAssay Description:Non-competitive inhibition of human LDHA assessed as reduction in lactate production using pyruvate as substrate in presence of NADH by Lineweaver-Bu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50532210(CHEBI:67078 | DELTA9-TETRAHYDROCANNABINOLIC ACID A)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of FAAH in rat brain membranes using [14C]-AEA as substrate measured after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50532210(CHEBI:67078 | DELTA9-TETRAHYDROCANNABINOLIC ACID A)
Affinity DataIC50:  2.73E+4nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in COS7 cells using [14C]-oleoyl-2-arachidonoyl-glycerol as substrate measured after 20 mins by b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50532210(CHEBI:67078 | DELTA9-TETRAHYDROCANNABINOLIC ACID A)
Affinity DataIC50:  150nMAssay Description:Antagonist activity at TRPM8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50532210(CHEBI:67078 | DELTA9-TETRAHYDROCANNABINOLIC ACID A)
Affinity DataIC50:  470nMAssay Description:Agonist activity at PPARgamma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50532210(CHEBI:67078 | DELTA9-TETRAHYDROCANNABINOLIC ACID A)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells using [14C]-N-palmitoylethanolamine as substrate measured after 30 mins by beta-counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed