BDBM50532251 CHEMBL4454373
SMILES COc1cc(ccc1Nc1ncc2C(=O)N3CCCCN=C3N(c3cccc(NC(=O)C=C)c3)c2n1)N1CCN(C)CC1
InChI Key InChIKey=DMUSMALBTMLQPZ-UHFFFAOYSA-N
Data 4 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50532251
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 17nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 0.880nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 0.880nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 17nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair