BDBM50532251 CHEMBL4454373

SMILES COc1cc(ccc1Nc1ncc2C(=O)N3CCCCN=C3N(c3cccc(NC(=O)C=C)c3)c2n1)N1CCN(C)CC1

InChI Key InChIKey=DMUSMALBTMLQPZ-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50532251   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50532251(CHEMBL4454373)
Affinity DataKd:  17nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50532251(CHEMBL4454373)
Affinity DataKd:  0.880nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50532251(CHEMBL4454373)
Affinity DataKd:  0.880nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50532251(CHEMBL4454373)
Affinity DataKd:  17nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed