BDBM50532254 CHEMBL4438135
SMILES CNN1CCN(CC1)c1ccc(Nc2ncc3c(n2)n(-c2cccc(NC(=O)C=C)c2)c2nccn2c3=O)c(OC)c1
InChI Key InChIKey=XWQVYGXYUOSECI-UHFFFAOYSA-N
Data 4 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50532254
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 310nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 2.60nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 2.60nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 310nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair