BDBM50532255 CHEMBL4464614
SMILES COc1cc(ccc1Nc1ncc2c(n1)n(-c1cccc(NC(=O)C=C)c1)c1nc3ccccc3n1c2=O)N1CCN(C)CC1
InChI Key InChIKey=SHPNSBFEVVBACD-UHFFFAOYSA-N
Data 4 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50532255
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 1.10nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 110nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 110nMAssay Description:Binding affinity to wild type partial length human EGFR expressed in bacterial system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dalian Medical University
Curated by ChEMBL
Dalian Medical University
Curated by ChEMBL
Affinity DataKd: 1.10nMAssay Description:Binding affinity to partial length human EGFR L858R/T790M double mutant expressed in mammalian system by KINOMEscan assayMore data for this Ligand-Target Pair