BDBM50532843 CHEMBL4545462

SMILES CCCCn1cc(C#N)c2c(c3C(=O)c4ccccc4-c3nc12)-c1ccc(cc1F)C(F)(F)F

InChI Key InChIKey=YLCHGUGGACXUSP-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50532843   

TargetReverse transcriptase(Human immunodeficiency virus 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532843(CHEMBL4545462)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 RT V108I mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532843(CHEMBL4545462)
Affinity DataIC50:  580nMAssay Description:Inhibition of HIV1 RT using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated for 10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532843(CHEMBL4545462)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 RT E138K using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532843(CHEMBL4545462)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 RT Y181C mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532843(CHEMBL4545462)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 RT E138K using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532843(CHEMBL4545462)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 RT V108I mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532843(CHEMBL4545462)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV1 RT Y181C mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532843(CHEMBL4545462)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of HIV1 RT K103N mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532843(CHEMBL4545462)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of HIV1 RT K103N mutant using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50532843(CHEMBL4545462)
Affinity DataIC50:  580nMAssay Description:Inhibition of HIV1 RT using 17-mer DNA/Alexa Fluor 488 5'-end labeled DNA/Alexa Fluor 555-aha-dUTP as primer/template/substrate preincubated for 10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed