BDBM50533716 CHEMBL4453504

SMILES [H][C@@]12C[C@@H]([C@H](CC)CN1CC[C@]21Nc2ccccc2C1=O)C(=C/OC)\C(=O)OC

InChI Key InChIKey=ZGFZEUQTWZGDLW-GHINOQSISA-N

Data  3 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50533716   

TargetMu-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533716(CHEMBL4453504)
Affinity DataKi:  0.460nMAssay Description:Displacement of [125I]-IBNtxA from mouse mu opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533716(CHEMBL4453504)
Affinity DataKi:  2.90nMAssay Description:Displacement of [125I]-IBNtxA from mouse delta opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533716(CHEMBL4453504)
Affinity DataKi:  19nMAssay Description:Displacement of [125I]-IBNtxA from mouse kappa opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533716(CHEMBL4453504)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at mouse mu opioid receptor-1 expressed in CHO cell membranes assessed as [35S]GTPgammaS binding incubated for 60 mins by scintillat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533716(CHEMBL4453504)
Affinity DataIC50:  193nMAssay Description:Antagonist activity at mouse delta opioid receptor-1 expressed in CHO cell membranes assessed as inhibition of DPDPE-induced [35S]GTPgammaS binding i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50533716(CHEMBL4453504)
Affinity DataIC50:  252nMAssay Description:Antagonist activity at mouse kappa opioid receptor-1 expressed in CHO cell membranes assessed as inhibition of U50,488H-induced [35S]GTPgammaS bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed