BDBM50534722 CHEMBL4549542
SMILES CN1CCN(C\C=C\C(=O)N2CCOc3cc4ncnc(Nc5ccc(F)c(Cl)c5)c4cc23)CC1
InChI Key InChIKey=JKIVVKXQGRWKDP-NSCUHMNNSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50534722
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Jiangsu Aosaikang Pharmaceutical
Curated by ChEMBL
Jiangsu Aosaikang Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 674nMAssay Description:Inhibition of HER2 (unknown origin) using FAM-labeled peptide substrate preincubated for 10 mins followed by substrate addition measured after 40 min...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangsu Aosaikang Pharmaceutical
Curated by ChEMBL
Jiangsu Aosaikang Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFR (unknown origin) using FAM-labeled peptide substrate preincubated for 10 mins followed by substrate addition measured after 40 min...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangsu Aosaikang Pharmaceutical
Curated by ChEMBL
Jiangsu Aosaikang Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human KB cells preincubated for 1 hr followed by EGF stimulation measured after 6 mins by ELISAMore data for this Ligand-Target Pair