BDBM50534734 CHEMBL2441561

SMILES Fc1ccc(Nc2ncnc3cc4OCCN(C(=O)\C=C\CN5CCOCC5)c4cc23)cc1Cl

InChI Key InChIKey=JWMBDFBXVNJSMO-OWOJBTEDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50534734   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Jiangsu Aosaikang Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50534734(CHEMBL2441561)
Affinity DataIC50:  996nMAssay Description:Inhibition of HER2 (unknown origin) using FAM-labeled peptide substrate preincubated for 10 mins followed by substrate addition measured after 40 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangsu Aosaikang Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50534734(CHEMBL2441561)
Affinity DataIC50:  7nMAssay Description:Inhibition of EGFR (unknown origin) using FAM-labeled peptide substrate preincubated for 10 mins followed by substrate addition measured after 40 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangsu Aosaikang Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50534734(CHEMBL2441561)
Affinity DataIC50:  146nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human KB cells preincubated for 1 hr followed by EGF stimulation measured after 6 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed