BDBM50534734 CHEMBL2441561
SMILES Fc1ccc(Nc2ncnc3cc4OCCN(C(=O)\C=C\CN5CCOCC5)c4cc23)cc1Cl
InChI Key InChIKey=JWMBDFBXVNJSMO-OWOJBTEDSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50534734
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Jiangsu Aosaikang Pharmaceutical
Curated by ChEMBL
Jiangsu Aosaikang Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 996nMAssay Description:Inhibition of HER2 (unknown origin) using FAM-labeled peptide substrate preincubated for 10 mins followed by substrate addition measured after 40 min...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangsu Aosaikang Pharmaceutical
Curated by ChEMBL
Jiangsu Aosaikang Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of EGFR (unknown origin) using FAM-labeled peptide substrate preincubated for 10 mins followed by substrate addition measured after 40 min...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangsu Aosaikang Pharmaceutical
Curated by ChEMBL
Jiangsu Aosaikang Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 146nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human KB cells preincubated for 1 hr followed by EGF stimulation measured after 6 mins by ELISAMore data for this Ligand-Target Pair