BDBM50535027 CHEMBL4571017
SMILES OC(=O)c1ccc(cc1)[C@H]1C[C@H](C[C@H](O1)c1ccccc1)NC(=O)C1(CC1)c1ccc2OC(F)(F)Oc2c1
InChI Key InChIKey=IWZSLCAIFMJGGT-OEMFJLHTSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50535027
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataEC50: 260nMAssay Description:Corrector activity at CFTR F508del mutant in human bronchial epithelial cells incubated for 18 to 24 hrs by TECC-based conductance assayMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataEC50: 300nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells incubated for 18 to 24 hrs by CSE-HRP assayMore data for this Ligand-Target Pair