BDBM50535442 CHEMBL4453882

SMILES COc1ccc(CCN(C)[C@@H]2CCC[C@@H](C2)N2CCc3cc(OC)c(OC)cc3CC2=O)cc1OC

InChI Key InChIKey=IUAVZEYOWYFRAS-RPWUZVMVSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50535442   

LigandPNGBDBM50535442(CHEMBL4453882)
Affinity DataEC50:  2.10E+4nMAssay Description:Inhibition of mouse HCN1 expressed in HEK293 cells assessed as reduction in hyperpolarization activated current at holding potential of -80 mV by pat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50535442(CHEMBL4453882)
Affinity DataEC50:  1.94E+4nMAssay Description:Inhibition of mouse HCN2 expressed in HEK293 cells assessed as reduction in hyperpolarization activated current at holding potential of -80 mV by pat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50535442(CHEMBL4453882)
Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of HCN4 in C57BL/6J mouse thalamocortical relay neuron assessed as reduction in hyperpolarization current at holding potential of -120 mV ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50535442(CHEMBL4453882)
Affinity DataEC50:  3.98E+3nMAssay Description:Inhibition of human HCN4 expressed in HEK293 cells assessed as reduction in hyperpolarization activated current at holding potential of -80 mV by pat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed