BDBM50535494 CHEMBL4527085

SMILES CC(C)(O)c1cnc(N)c2nc(ccc12)-c1ccnc(F)c1

InChI Key InChIKey=XVUSMHCLFMFBQR-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50535494   

TargetMisshapen-like kinase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535494(CHEMBL4527085)
Affinity DataIC50:  200nMAssay Description:Inhibition of human 6His-TEV-Avi-MINK1(1 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535494(CHEMBL4527085)
Affinity DataIC50:  126nMAssay Description:Inhibition of human 6His-TEV-TNIK(1 to 325) expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50535494(CHEMBL4527085)
Affinity DataIC50:  158nMAssay Description:Inhibition of human 6His-TEV-SHM-MAP4K4(2 to 328)-GNS expressed in baculovirus-infected sf21 cells using LRRKtide as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB