BDBM50535648 CHEMBL4450014

SMILES C[C@H]1CN(CCN1C1COC1)c1cc(ncn1)-n1ncc2ccc(cc12)C1(CC2(CC2)C1)C#N

InChI Key InChIKey=UTCLNEFWKHZBPP-SFHVURJKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50535648   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50535648(CHEMBL4450014)
Affinity DataIC50:  1nMAssay Description:Inhibition of GST-tagged truncated human LRRK2 G2019S mutant pre-incubated for 15 mins before fluorescein-labeled peptide substrate LRRKtide addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed