BDBM50535847 CHEMBL4541898

SMILES CCCCCCC(=O)N1CCc2c(C1)c(nn2C)-c1ccc(cc1)C(C)(C)C(O)=O

InChI Key InChIKey=XFBAMRWEUKVTJU-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535847   

TargetSerine palmitoyltransferase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50535847(CHEMBL4541898)
Affinity DataIC50:  64nMAssay Description:Inhibition of human SPT1 expressed in microsomes of HEK293 cells incubated for 1hr by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine palmitoyltransferase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50535847(CHEMBL4541898)
Affinity DataEC50:  4.22E+3nMAssay Description:Inhibition of SPT1 in human MCF7 cells assessed as suppression of 14C-serine incorporation into ceramide incubated for 2 hrs in presence of 4-HPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed