BDBM50535969 CHEMBL4543897
SMILES CCC(CC)CNc1c(cnc2ccc(cc12)-c1cccnc1)C(N)=O
InChI Key InChIKey=KHOSFSGTKQFGDP-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50535969
Affinity DataIC50: 73nMAssay Description:Inhibition of ATM phosphorylation at Ser-1981 residue in human HT-29 cells incubated for 1 hr followed by X-ray irradiation by Hoechst staining based...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of human ERG by electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of ATR in human HT-29 cells assessed as reduction in Chk1 phosphorylation at Ser-345 residue after 60 mins in presence of 4-nitroquinoline...More data for this Ligand-Target Pair