BDBM50536362 CHEMBL4517346

SMILES COc1ccccc1Nc1nc(cs1)-c1sc(NC(C)=O)nc1C

InChI Key InChIKey=ZADCDCMLLGDCRM-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50536362   

TargetSerine/threonine-protein kinase TAO2(Rattus norvegicus)
University Of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM50536362(CHEMBL4517346)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50536362(CHEMBL4517346)
Affinity DataIC50:  440nMAssay Description:Inhibition of MMP-9 (unknown origin) using Cys(Eu)-Pro-Leu-Gly-Leu-Lys(QSY7)-Ala-Arg-amide as substrate for 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50536362(CHEMBL4517346)
Affinity DataIC50:  440nMAssay Description:Inhibition of human proMMP9 expressed in African green monkey COS-1 cells assessed as reduction in protein activation incubated for 30 mins prior to ...More data for this Ligand-Target Pair